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Original ArticleOpen Access
Prevention of Antibiotic-Associated Diarrhea in Infants by Probiotics
Jirapinyo P 
,
Densupsoontom N ,
Thamonsiri N ,
Wongam R
,
Densupsoontom N ,
Thamonsiri N ,
Wongam R Probiotics administration has been claimed to prevent antibiotic -associated diarrhea. The
investigators thus conducted a double blind, placebo controlled study of providing probiotics to
infants and children with severe bacterial infections and receiving broad spechum antibiotics.
The results of the study showed that the group receiving probiotics had fewer diarrheal
episodes (37.5%) than the control group (80%), although the numbers were too small for statistical
analysis. In conclusion, probiotics administration to patients receiving high doses of broad spectrum
antibiotics may prevent the occurrence of antibiotic-associated diarrhea. A further study with a larger
number is required.
Key word : Probiotics, Antibiotic-Associated Diarrhea
investigators thus conducted a double blind, placebo controlled study of providing probiotics to
infants and children with severe bacterial infections and receiving broad spechum antibiotics.
The results of the study showed that the group receiving probiotics had fewer diarrheal
episodes (37.5%) than the control group (80%), although the numbers were too small for statistical
analysis. In conclusion, probiotics administration to patients receiving high doses of broad spectrum
antibiotics may prevent the occurrence of antibiotic-associated diarrhea. A further study with a larger
number is required.
Key word : Probiotics, Antibiotic-Associated Diarrhea
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