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Original ArticleOpen Access
Mental State Change after General and Regional Anesthesia in Adults and Elderly Patients,a Randomezed Clinecal Trial
Somprakit P 
,
Lertakyamanee J ,
Sattaratanamai C ,
Wanicksamban S ,
Silapadech A ,
Chainchop P ,
Muangsuay V
,
Lertakyamanee J ,
Sattaratanamai C ,
Wanicksamban S ,
Silapadech A ,
Chainchop P ,
Muangsuay V JARIYA LERTAKYAMANEE, M.D.*,
SIWAPORN WANICKSAMBAN, M.D.*,
PHETCHAREE CHAINCHOP, B.N. *,
Background : Mental state changes after anesthesia seemed to be more frequent in older
patients, but the results were still unclear.
Objective : To compare the mental scores between adults and elderly patients after general
and regional anesthesia.
Methods : This was a stratified randomized trial with factorial design. Sixty
patients~
60
years old and sixty patients
<
60 years old were randomly assigned to receive general or regional
anesthesia. Their mental states were assessed blind by investigators, using the Thai Mental State
Examination score.
Results : The two anesthetic groups showed no difference in the mental scores, but the two
age groups showed significantly different scores. The components of mental states that were signifi-
cantly different were orientation and recall. There were no significant differences in registration,
attention, calculation and language. The model for predicting the score included age, education level
and narcotics given within six hours before assessment. Sex, weight, intraoperative hypotension,
blood loss and duration of anesthesia could not explain the change in the scores.
Conclusion : Age, but not anesthetic technique, affected the mental scores after anesthesia.
Key word : Anesthetic Technique, General Anesthesia, Regional Anesthesia, Mental State Change
in Adults and Elderly Patients
SIWAPORN WANICKSAMBAN, M.D.*,
PHETCHAREE CHAINCHOP, B.N. *,
Background : Mental state changes after anesthesia seemed to be more frequent in older
patients, but the results were still unclear.
Objective : To compare the mental scores between adults and elderly patients after general
and regional anesthesia.
Methods : This was a stratified randomized trial with factorial design. Sixty
patients~
60
years old and sixty patients
<
60 years old were randomly assigned to receive general or regional
anesthesia. Their mental states were assessed blind by investigators, using the Thai Mental State
Examination score.
Results : The two anesthetic groups showed no difference in the mental scores, but the two
age groups showed significantly different scores. The components of mental states that were signifi-
cantly different were orientation and recall. There were no significant differences in registration,
attention, calculation and language. The model for predicting the score included age, education level
and narcotics given within six hours before assessment. Sex, weight, intraoperative hypotension,
blood loss and duration of anesthesia could not explain the change in the scores.
Conclusion : Age, but not anesthetic technique, affected the mental scores after anesthesia.
Key word : Anesthetic Technique, General Anesthesia, Regional Anesthesia, Mental State Change
in Adults and Elderly Patients
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