J Med Assoc Thai 2002; 85 (9):910

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Neuropsychological Alterations After Coronary Artery Bypass Graft Surgery
Suksompong S Mail, Chumpathong S , Pornvilawan S , Prakanrattana U , Sriyoschati S

UNGKAB PRAKANRATTANA,M.D.*,
SOMCHAI SRIYOSCHATI, M.D.**,
Objective : To evaluate neuropsychological dysfunction in patients following elective coro-
nary artery bypass graft surgery at Siriraj Hospital.
Patients and Method : One hundred and ten patients who were scheduled for elective
coronary artery bypass graft surgery were included in this study. We used the Thai Mental State
Examination (TMSE) in order to detect the presence of cognitive impainnent after coronary artery
bypass graft surgery. The examinations were conducted on two consecutive occasions; first preopera-
tively, the day before surgery, secondly on the third-fifth postoperative day. The patients' clinical
characteristics were assessed perioperatively.
Results : The overall occurrence of neuropsychological deficit was 18.18 per cent. Pre-
dictors of neuropsychological dysfunction were older age and preexisting disease such as hypertension,
hypercholesterolemia and renal insufficiency. Other risk factors such as gender, history of congestive
heart failure, myocardial infarction, diabetes mellitus, dysrhythmia, cardiopulmonary bypass time,
hemoglobin during cardiopulmonary bypass

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