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Original ArticleOpen Access
Accuracy of Glucose Meters in Measuring Low Blood Glucose Levels
Choubtum L 
,
Mahachoklertwattana P ,
Udomsubpayakul U ,
Preeyasombat C
,
Mahachoklertwattana P ,
Udomsubpayakul U ,
Preeyasombat C Background : Hypoglycemia is an emergency condition requiring treatment as soon as
possible. Therefore, rapid and reliable blood glucose measurements are necessary. There are 2 systems
of glucose meters (GMs), the reflectance photometer system (RPS) and the electrochemical
biosensor system (BSS). GMs are widely used in monitoring blood glucose (BG) in patients with
diabetes. BG values measured by GMs have been confirmed to be accurate especially in measuring
normal and high BG levels. However, the data on the accuracy of GMs in measuring low BG levels
are limited.
Objective : To compare accuracy and reliability of different systems of GMs in the measurement
of low BG values.
Patients and Method : Venous and capillary whole blood specimens were collected from
patients who were investigated for pituitary dysfunction. The patients underwent an insulin-induced
hypoglycemia test by intravenously administering human regular insulin. The low BG level was
defined as having venous plasma glucose (PG) of Jess than 60 mg/dl (mean± SD = 36.59 ± 9.19, n =
54). Capillary blood samples were obtained from fingertips. Venous BG (vBG) and capillary BG
(cBG) were measured by GMs. Venous PG which considered a reference value was measured by the
glucose dehydrogenase method.
Results : The correlation coefficient (r) between vBG measured by GMs-RPS and PG was
0.86 (p
possible. Therefore, rapid and reliable blood glucose measurements are necessary. There are 2 systems
of glucose meters (GMs), the reflectance photometer system (RPS) and the electrochemical
biosensor system (BSS). GMs are widely used in monitoring blood glucose (BG) in patients with
diabetes. BG values measured by GMs have been confirmed to be accurate especially in measuring
normal and high BG levels. However, the data on the accuracy of GMs in measuring low BG levels
are limited.
Objective : To compare accuracy and reliability of different systems of GMs in the measurement
of low BG values.
Patients and Method : Venous and capillary whole blood specimens were collected from
patients who were investigated for pituitary dysfunction. The patients underwent an insulin-induced
hypoglycemia test by intravenously administering human regular insulin. The low BG level was
defined as having venous plasma glucose (PG) of Jess than 60 mg/dl (mean± SD = 36.59 ± 9.19, n =
54). Capillary blood samples were obtained from fingertips. Venous BG (vBG) and capillary BG
(cBG) were measured by GMs. Venous PG which considered a reference value was measured by the
glucose dehydrogenase method.
Results : The correlation coefficient (r) between vBG measured by GMs-RPS and PG was
0.86 (p
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