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Original ArticleOpen Access
Henoch-Schonlein Purpura : Clinical Manifestations and Long-Term Outcomes in Thai Children
Pabunruang W 
,
Treepongkaruna S ,
Tangnararatchakit K ,
Chunharas A ,
Phuapradit P
,
Treepongkaruna S ,
Tangnararatchakit K ,
Chunharas A ,
Phuapradit P The clinical features of 47 children with Henoch-Schonlein purpura (HSP) are presented.
The most common ages at presentation ranged from 3-5 years. Duration of data collection was 60
months. The peak incidence was from December to February. The organ involvements included skin
(100%), gastrointestinal tract (74.5%), renal (46.8%) and joint (42.6%). Renal involvement was
detected within the first 2 months in 16 cases (72.7%) but was delayed until 6 months after diagnosis
in 6 cases. No risk factors for renal involvement could be identified. The mean duration of follow-up
was 2.6 years (range 1-5 years). Six out of 16 (37.5%) patients had residual renal diseases but
none were end stage. Recurrent episodes of abdominal pain and skin purpura were found in a few
cases during the first year.
Overall prognosis of HSP is good and long-term morbidity is predominantly associated with
renal involvement. Patients with initially normal urinalysis should have sequential urinary examination
at least for 6 months.
Key word : Henoch-Schonlein Purpura, IgA Nephropathy, Nephrotic Syndrome, Proteinuria, Hypertension
The most common ages at presentation ranged from 3-5 years. Duration of data collection was 60
months. The peak incidence was from December to February. The organ involvements included skin
(100%), gastrointestinal tract (74.5%), renal (46.8%) and joint (42.6%). Renal involvement was
detected within the first 2 months in 16 cases (72.7%) but was delayed until 6 months after diagnosis
in 6 cases. No risk factors for renal involvement could be identified. The mean duration of follow-up
was 2.6 years (range 1-5 years). Six out of 16 (37.5%) patients had residual renal diseases but
none were end stage. Recurrent episodes of abdominal pain and skin purpura were found in a few
cases during the first year.
Overall prognosis of HSP is good and long-term morbidity is predominantly associated with
renal involvement. Patients with initially normal urinalysis should have sequential urinary examination
at least for 6 months.
Key word : Henoch-Schonlein Purpura, IgA Nephropathy, Nephrotic Syndrome, Proteinuria, Hypertension
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