J Med Assoc Thai 2002; 85 (11):1219

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Vitamin A Status in Premature Infants
Feungpean B Mail, Suthutvoravut U , Supapannachart S , Rakthai S , Chatvuttinun S

Background : Premature infants are at risk of vitamin A deficiency due to inadequate
transplacental transport, inadequate storage and increased tissue utilization. Previous studies reported
a significant decrease in serum vitamin A levels in premature infants at birth compared to those of
full term infants.
Objective : To determine serial changes of plasma vitamin A status during the first month
of life in 19 healthy, very low birth weight premature infants.
Method : Subjects were fed with premature infant formula and received multivitamin
supplementation. Plasma vitamin A concentrations were measured at 7, 14, and 30 days of age.
Results : Plasma vitamin A levels at 7, 14 and 30 days of age were 24.63 ± 6.08, 30.97 ±
5.26 and 30.68 ± 7.14 µg/dl, respectively. Plasma vitamin A levels at age 7 days were significantly
lower than those at 14 and 30 days of life (p

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