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Case ReportOpen Access
Sebaceous Nevus Syndrome as the Underlying Cause of Intractable Seizures in a One-Month-Old Infant
Visudtibhan A 
,
Chiemchanya S ,
Chunharas A ,
Kitiviriyakul D ,
Visudhiphan P
,
Chiemchanya S ,
Chunharas A ,
Kitiviriyakul D ,
Visudhiphan P A one-month-old male infant with generalized seizures since 2 days old was evaluated
at the Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University,
Bangkok, Thailand. His seizures were initially characterized as focal ,movement of the right upper
and lower limbs followed by generalized tonic. Initially, phenobarbital was administered but failed
to control his seizures. Physical examination revealed generalized mild hypotonia with a hyperpigmented
brownish patch affecting the left side of his face. The initial diagnosis was sebaceous nevus
syndrome which is one of the neurocutaneous syndromes. The. diagnosis was confirmed by skin
biopsy of the affected lesion. The literature was reviewed and discussed. The authors emphasized
the importance of thorough physical examination including evaluation of specific skin lesion which
would be a leading clue in making the diagnosis of symptomatic epilepsy in infants.
Key word : Sebaceous Nevus Syndrome, Intractable Seizures
at the Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University,
Bangkok, Thailand. His seizures were initially characterized as focal ,movement of the right upper
and lower limbs followed by generalized tonic. Initially, phenobarbital was administered but failed
to control his seizures. Physical examination revealed generalized mild hypotonia with a hyperpigmented
brownish patch affecting the left side of his face. The initial diagnosis was sebaceous nevus
syndrome which is one of the neurocutaneous syndromes. The. diagnosis was confirmed by skin
biopsy of the affected lesion. The literature was reviewed and discussed. The authors emphasized
the importance of thorough physical examination including evaluation of specific skin lesion which
would be a leading clue in making the diagnosis of symptomatic epilepsy in infants.
Key word : Sebaceous Nevus Syndrome, Intractable Seizures
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