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Case ReportOpen Access
Thrombocytopenic Purpura Associated with Miliary Tuberculosis
Tongyoo S 
,
Vilaichone W ,
Sukpanichnant S ,
Auewarakul C ,
Chaiprasert A ,
Ratanarat R ,
Permpikul C
,
Vilaichone W ,
Sukpanichnant S ,
Auewarakul C ,
Chaiprasert A ,
Ratanarat R ,
Permpikul C WARAKARN VILAICHONE, MD*,
CHIRAYU AUEWARAKUL,MD***,
RANIS TNA RA TANARA T, MD*,
The authors report a case of thrombocytopenia associated with miliary tuberculosis. The patient
was a 28-year-old woman who was admitted because of massive upper gastrointestinal hemorrhage
and acute respiratory failure. Chest radiographs revealed diffuse bilateral reticulonodular infiltration
and complete blood count was significant for severe thrombocytopenia. Bone marrow biopsy was
performed to investigate the cause of thrombocytopenia and demonstrated multiple tiny caseating
granulomas suggesting miliary tuberculosis (TB). She received anti-TB therapy and a short course of
steroid with good response. Platelet count returned to normal limit within 10 days. Although isolated
thrombocytopenia is uncommon in TB, it is still important to consider TB in the differential Jiagnosis
of thrombocytopenia, particularly in patients with abnormal chest radiographs. Bone marrow examina-
tion is very helpful in this situation.
Key word : Miliary Tuberculosis, Thrombocytopenia, Hemorrhage
CHIRAYU AUEWARAKUL,MD***,
RANIS TNA RA TANARA T, MD*,
The authors report a case of thrombocytopenia associated with miliary tuberculosis. The patient
was a 28-year-old woman who was admitted because of massive upper gastrointestinal hemorrhage
and acute respiratory failure. Chest radiographs revealed diffuse bilateral reticulonodular infiltration
and complete blood count was significant for severe thrombocytopenia. Bone marrow biopsy was
performed to investigate the cause of thrombocytopenia and demonstrated multiple tiny caseating
granulomas suggesting miliary tuberculosis (TB). She received anti-TB therapy and a short course of
steroid with good response. Platelet count returned to normal limit within 10 days. Although isolated
thrombocytopenia is uncommon in TB, it is still important to consider TB in the differential Jiagnosis
of thrombocytopenia, particularly in patients with abnormal chest radiographs. Bone marrow examina-
tion is very helpful in this situation.
Key word : Miliary Tuberculosis, Thrombocytopenia, Hemorrhage
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