Views: 1,384 | Downloads:
22
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Original ArticleOpen Access
Low Dose, One-Week Triple Therapy (Lanzoprazole, Amoxycillin, Clarithromycin for Eradication of Helicobacter pylori Infection
Uthaisaengsook W 
Objective
: To evaluate the efficacy and safety of low dose one week triple therapy with lanso-
prazole, amoxycillin and clarithromycin for the eradication of
Helicobacter pylori
(H.
pylori).
Method
: A total of 103 patients with
H.
pylori
infection who had gastritis, duodenal ulcer
(DU) or gastric ulcer (GU) received 1 week's triple therapy of lansoprazole 30 g once daily (OD).
amoxycillin 250 mg qid and clarithromycin 250 mg tid. The status of
H.
pylori
infection was determined
using the CLO test and histology (gram stain) of biopsy specimens during endoscopic examination.
Result
: After treatment with triple therapy
H.
pylori
infection was eradicated in 98 of 103
patients (95.15% ), dyspeptic symptoms and upper gastrointestinal hemorrhage improved in 99 of 103
patients (96.1% ). No adverse effect was observed in all the patients was received treatment.
Conclusion
: Low dose one-week triple therapy with lansoprazole, amoxycillin and clari-
thromycin is effective for eradication of
H.
pylori
infection.
Key word
:
Helicobacter pylori,
Triple Therapy
: To evaluate the efficacy and safety of low dose one week triple therapy with lanso-
prazole, amoxycillin and clarithromycin for the eradication of
Helicobacter pylori
(H.
pylori).
Method
: A total of 103 patients with
H.
pylori
infection who had gastritis, duodenal ulcer
(DU) or gastric ulcer (GU) received 1 week's triple therapy of lansoprazole 30 g once daily (OD).
amoxycillin 250 mg qid and clarithromycin 250 mg tid. The status of
H.
pylori
infection was determined
using the CLO test and histology (gram stain) of biopsy specimens during endoscopic examination.
Result
: After treatment with triple therapy
H.
pylori
infection was eradicated in 98 of 103
patients (95.15% ), dyspeptic symptoms and upper gastrointestinal hemorrhage improved in 99 of 103
patients (96.1% ). No adverse effect was observed in all the patients was received treatment.
Conclusion
: Low dose one-week triple therapy with lansoprazole, amoxycillin and clari-
thromycin is effective for eradication of
H.
pylori
infection.
Key word
:
Helicobacter pylori,
Triple Therapy
Download:
PDF