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Original ArticleOpen Access
Hyperthermia in Combination with Radiation Therapy for Treatment of Advanced Inoperable Breast Cancer
N 
,
Pattaranutaporn MP ,
Chansilpa Y ,
Sukkasem M
,
Pattaranutaporn MP ,
Chansilpa Y ,
Sukkasem M Twelve breast cancer patients with locally advanced inoperable lesions were studied. Six
cases had received chemotherapy, 6 had not. Most of the tumors were ulcerative lesions with an average
size of 11.5 em. The patients were treated with 43"C hyperthermia once or twice a week together with
radiation at a dose of 20-70 Gy. Six of them were also treated with concurrent chemotherapy. Two
cases responded completely ( 17%) and 10 cases responded partially (83% ). The result indicates that the
combination of hyperthermia and radiation, with or without chemotherapy, might be a good treatment
option for locally advanced inoperable breast cancer, especially for patients who have had failure or
contraindication to chemotherapy. It is an effective treatment for palliation of local symptoms, show-
ing a tendency to achieve local control of large, ulcerative advanced breast lesions especially when
such treatment is followed by salvage surgery.
Key word : Breast Cancer, Hyperthermia, Radiation Therapy
cases had received chemotherapy, 6 had not. Most of the tumors were ulcerative lesions with an average
size of 11.5 em. The patients were treated with 43"C hyperthermia once or twice a week together with
radiation at a dose of 20-70 Gy. Six of them were also treated with concurrent chemotherapy. Two
cases responded completely ( 17%) and 10 cases responded partially (83% ). The result indicates that the
combination of hyperthermia and radiation, with or without chemotherapy, might be a good treatment
option for locally advanced inoperable breast cancer, especially for patients who have had failure or
contraindication to chemotherapy. It is an effective treatment for palliation of local symptoms, show-
ing a tendency to achieve local control of large, ulcerative advanced breast lesions especially when
such treatment is followed by salvage surgery.
Key word : Breast Cancer, Hyperthermia, Radiation Therapy
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