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Original ArticleOpen Access
Result of Orthotopic Liver Transplantation at King Chulalongkorn Memorial Hospital : The First Series From Thailand
Nivatvongs S 
,
Sirichindakul B ,
Nontasuti B ,
Kongkam P ,
Rerknimitr R ,
Kullavanijaya P
,
Sirichindakul B ,
Nontasuti B ,
Kongkam P ,
Rerknimitr R ,
Kullavanijaya P BOONCHOO SIRICHINDAKUL, MD*,
PRADERMCHAI KONGKAM, MD**,
PINIT KULLA V ANUAYA, MD**
Liver transplantation is one of the best treatments for advanced liver disease since it can
prolong the patient's survival. In Thailand, the first liver transplantation was performed in 1987 at
King Chulalongkom Memorial Hospital. Up till now the authors have transplanted the most in Thai-
land, having done more than 30 cases.
From 1997 to 2002, there were 20 cases of liver transplantation and this is the result is pre-
sented. The authors classified the patients into 2 groups, according to primary indications for trans-
plantation. Patients with cirrhosis were included in group I and patients with hepatocellular carcinoma
were included in group II. The one year survival in group I and II was 64 per cent and 29 per cent
respectively. Mortality rate in the cirrhotic group was high during the first 3 months post transplant.
The reason for a high mortality rate in the hepatocellular carcinoma group may be secondary to the
advanced stage of cancer and the poor condition of the patients. However, the acute rejection rate in
the present series of 25 per cent is relatively low compared to other series and this may need further
study.
The one year survival rate in patients who received a new liver from 1997 to 1999 compared
to 2000-2002 was 33 per cent and 54 per cent respectively. This showed an improvement in the result
of liver transplantation in Thailand.
In conclusion, this report showed a satisfactory result of liver transplantation. The main pro-
blem with liver transplantation in Thailand is that potential donors do not understand the problems
which leads to few donors. There is also a shortage of skilled personnel, budget, and the appropriate
instruments.
Key word : Liver Transplantation, Thailand, Survival
PRADERMCHAI KONGKAM, MD**,
PINIT KULLA V ANUAYA, MD**
Liver transplantation is one of the best treatments for advanced liver disease since it can
prolong the patient's survival. In Thailand, the first liver transplantation was performed in 1987 at
King Chulalongkom Memorial Hospital. Up till now the authors have transplanted the most in Thai-
land, having done more than 30 cases.
From 1997 to 2002, there were 20 cases of liver transplantation and this is the result is pre-
sented. The authors classified the patients into 2 groups, according to primary indications for trans-
plantation. Patients with cirrhosis were included in group I and patients with hepatocellular carcinoma
were included in group II. The one year survival in group I and II was 64 per cent and 29 per cent
respectively. Mortality rate in the cirrhotic group was high during the first 3 months post transplant.
The reason for a high mortality rate in the hepatocellular carcinoma group may be secondary to the
advanced stage of cancer and the poor condition of the patients. However, the acute rejection rate in
the present series of 25 per cent is relatively low compared to other series and this may need further
study.
The one year survival rate in patients who received a new liver from 1997 to 1999 compared
to 2000-2002 was 33 per cent and 54 per cent respectively. This showed an improvement in the result
of liver transplantation in Thailand.
In conclusion, this report showed a satisfactory result of liver transplantation. The main pro-
blem with liver transplantation in Thailand is that potential donors do not understand the problems
which leads to few donors. There is also a shortage of skilled personnel, budget, and the appropriate
instruments.
Key word : Liver Transplantation, Thailand, Survival
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