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Original ArticleOpen Access
D-Xylose Absorption in Non-Chronic Diarrhea AIDS Patients with the Wasting Syndrome
Luangjaru S 
,
Ruxrungtham K ,
Wisedopas N ,
Mahachai V
,
Ruxrungtham K ,
Wisedopas N ,
Mahachai V KAIT RUXRUNGTHAM, MD**,
V AROCHA MAHACHAI, MD**
Objective
: To compare the intestinal absorptive capacity, permeability function and duo-
denal histopathology in human immunodeficiency virus (HIV) patients with or without wasting syn-
drome who had not suffered from chronic diarrhea.
Method
: Adult HIV patients who attended Chulalongkom Hospital were included. The sub-
jects were classified into wasting and non-wasting groups (group I and group II). 25 g oral D-xylose
test, oral phenolsulfonephthalein test and duodenal histopathology were performed.
Results
: Of thirty-two HIV patients, aged between 25-50 years enrolled, there were 18 and
14 patients in group I and group II, respectively. In both groups, the baseline data, permeability func-
tion and histopathology were similar. Intestinal absorptive capacity was statistically different, i.e. 5-
hour urine D-xylose was 3.96
เธ‘
2.81 g and 5.95
เธ‘
2.47 gin group I and group II respectively (p <
0.05).
Conclusion
: This study demonstrated that D-xylose absorption was decreased in non-diar-
rheal, wasting HIV infected patients. Abnormal absorptive capacity is a common phenomenon found
in HIV patients with wasting syndrome as determined by standard 25 g oral D-xylose test.
Key word
: D-xylose Absorption, Permeability Function, HIV Wasting Syndrome
V AROCHA MAHACHAI, MD**
Objective
: To compare the intestinal absorptive capacity, permeability function and duo-
denal histopathology in human immunodeficiency virus (HIV) patients with or without wasting syn-
drome who had not suffered from chronic diarrhea.
Method
: Adult HIV patients who attended Chulalongkom Hospital were included. The sub-
jects were classified into wasting and non-wasting groups (group I and group II). 25 g oral D-xylose
test, oral phenolsulfonephthalein test and duodenal histopathology were performed.
Results
: Of thirty-two HIV patients, aged between 25-50 years enrolled, there were 18 and
14 patients in group I and group II, respectively. In both groups, the baseline data, permeability func-
tion and histopathology were similar. Intestinal absorptive capacity was statistically different, i.e. 5-
hour urine D-xylose was 3.96
เธ‘
2.81 g and 5.95
เธ‘
2.47 gin group I and group II respectively (p <
0.05).
Conclusion
: This study demonstrated that D-xylose absorption was decreased in non-diar-
rheal, wasting HIV infected patients. Abnormal absorptive capacity is a common phenomenon found
in HIV patients with wasting syndrome as determined by standard 25 g oral D-xylose test.
Key word
: D-xylose Absorption, Permeability Function, HIV Wasting Syndrome
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