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Original ArticleOpen Access
Out-Patient Antibiotics Switch Therapy in Pediatric Urinary Tract Infection
Bunnag T 
,
Kietkajornkul C
,
Kietkajornkul C THANYANAT BUNNAG, MD*,
CHOOKIET KIETKAJORNKUL, MD*
Objective : To compare the outcomes of out-patient antibiotics switch therapy with the treat-
ment provided in the hospital among pediatric urinary tract infection (UTI) cases.
Material and Method :A comparative study was carried out using the febrile UTI patients of
age 1 month-15 years in the observation room (OPD), Queen Sirikit National Institute of Child Health,
Bangkok, Thailand, from 1" January 2000 to 31" December 2000 and the admitted pediatric UTI cases
during the same period. The treatment at the OPD was started with parenteral antibiotics, then switched
to oral form when the patients were clinically improved and defervesence occurred.
Results : There were 95 cases of pediatric UTI of which 29 cases were treated in the observa-
tion room as out-patient, 66 cases were treated as in patients after admitting them. The success rate of
treatment was the same in both groups. The patients in the observation room were fit enough to be
discharged but continued oral treatment within 1.93
เธ‘
0.65 days, compared with 6.24
เธ‘
2.72 days of
the admitted group. Gentamicin and ceftriazone were the two most common parenteral antibiotics and
norfloxacin was the most commonly prescribed oral antibiotics in both group. Mean age of the OPD
group (6.24
เธ‘
2. 72 years) was higher than the admitted group (0.97
เธ‘
1.7
year).
Escherichia coli
(E.
coli)
was the most commonly found organism in the urine culture and the sensitivity pattern was the same
in both groups.
Conclusion : The study revealed that some pediatric UTI patients can be treated as out-patients
using antibiotics switch therapy in the observation room instead of being admitted.
Key word : Urinary Tract Infection, Antibiotics Switch Therapy
CHOOKIET KIETKAJORNKUL, MD*
Objective : To compare the outcomes of out-patient antibiotics switch therapy with the treat-
ment provided in the hospital among pediatric urinary tract infection (UTI) cases.
Material and Method :A comparative study was carried out using the febrile UTI patients of
age 1 month-15 years in the observation room (OPD), Queen Sirikit National Institute of Child Health,
Bangkok, Thailand, from 1" January 2000 to 31" December 2000 and the admitted pediatric UTI cases
during the same period. The treatment at the OPD was started with parenteral antibiotics, then switched
to oral form when the patients were clinically improved and defervesence occurred.
Results : There were 95 cases of pediatric UTI of which 29 cases were treated in the observa-
tion room as out-patient, 66 cases were treated as in patients after admitting them. The success rate of
treatment was the same in both groups. The patients in the observation room were fit enough to be
discharged but continued oral treatment within 1.93
เธ‘
0.65 days, compared with 6.24
เธ‘
2.72 days of
the admitted group. Gentamicin and ceftriazone were the two most common parenteral antibiotics and
norfloxacin was the most commonly prescribed oral antibiotics in both group. Mean age of the OPD
group (6.24
เธ‘
2. 72 years) was higher than the admitted group (0.97
เธ‘
1.7
year).
Escherichia coli
(E.
coli)
was the most commonly found organism in the urine culture and the sensitivity pattern was the same
in both groups.
Conclusion : The study revealed that some pediatric UTI patients can be treated as out-patients
using antibiotics switch therapy in the observation room instead of being admitted.
Key word : Urinary Tract Infection, Antibiotics Switch Therapy
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