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Original ArticleOpen Access
Vertical Transmission of Dengue Infection in Thai Infants: Two Case Reports
Chotigeat U 
,
Kalayanarooj S ,
Nisalak A
,
Kalayanarooj S ,
Nisalak A URAIWAN CHOTIGEAT, MD*,
SIRIPEN KALA Y ANAROOJ, MD**,
ANANDA NISALAK, MD***
Dengue infection is hyperendemic in tropical countries especially in Thailand. Most dengue
infections occur during childhood but some adults may remain susceptible to infection. About 30 per
cent of dengue infection are reported in patients> 15 years old. Some pregnant women may also be
susceptible to dengue and if they experience dengue infection, they can transmit the dengue viruses
to their babies. The authors report two babies who developed mild dengue illness, dengue hemorrhagic
fever (DHF) grade II, beginning on their
6'h
day of life. Both of them had low grade fever, hepatomegaly
and generalized petechial rash. The first baby had Hct ranging from 46 to 40 per cent with minimal
right pleural effusion. The lowest platelet count was 19,000 cells/mm
3
*
His mother had dengue shock
syndrome with masssive post partum bleeding. The second baby had dengue 2 infection while his
mother had dengue fever. His Hct had also risen from 52 per cent to 61 per cent with right pleural
effusion. His lowest platelet count was 7,000 cells/mm
3
*
Both mothers and their babies had a complete
recovery although the first baby had prolonged thrombocytopenia for two months.
Key word : Vertical Transmission, Dengue Infection
SIRIPEN KALA Y ANAROOJ, MD**,
ANANDA NISALAK, MD***
Dengue infection is hyperendemic in tropical countries especially in Thailand. Most dengue
infections occur during childhood but some adults may remain susceptible to infection. About 30 per
cent of dengue infection are reported in patients> 15 years old. Some pregnant women may also be
susceptible to dengue and if they experience dengue infection, they can transmit the dengue viruses
to their babies. The authors report two babies who developed mild dengue illness, dengue hemorrhagic
fever (DHF) grade II, beginning on their
6'h
day of life. Both of them had low grade fever, hepatomegaly
and generalized petechial rash. The first baby had Hct ranging from 46 to 40 per cent with minimal
right pleural effusion. The lowest platelet count was 19,000 cells/mm
3
*
His mother had dengue shock
syndrome with masssive post partum bleeding. The second baby had dengue 2 infection while his
mother had dengue fever. His Hct had also risen from 52 per cent to 61 per cent with right pleural
effusion. His lowest platelet count was 7,000 cells/mm
3
*
Both mothers and their babies had a complete
recovery although the first baby had prolonged thrombocytopenia for two months.
Key word : Vertical Transmission, Dengue Infection
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