J Med Assoc Thai 2003; 86 (8):741

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Can Octreotide be the First Line Treatment for Chylothorax?
Leelahanon S Mail, Petlek W , Sontimuang W , Pochanart P , Tepakorn V , Ruangpeg S

WATTANASAK PETLEK, MD**,
PAKPOOM POCHANART, MD**,
SA TIT RUANGPEG, MD**
Background
: Chylothorax is a rare but serious condition with a high rate of morbidity that
may lead to death.
It
may be spontaneous or a complication of cardiac surgery. Treatment of this
potentially harmful condition is not well established and may comprise dietary interventions. In order
to avoid surgery, somatostatin and octreotide have been recently suggested as new modalities for the
treatment of chylothorax.
Objective:
To study the efficacy of octreotide for the treatment of chylothorax.
Method:
Cases reports.
Result
: The authors report two cases of chylothorax successfully treated with intravenous
infusion of octreotide as an adjunct to conventional treatment. Furthermore, the authors report their last
case who were treated successfully with octreotide as the first line drug without diet modification.
Conclusion
: It seems that octreotide is effective, noninvasive and safe. It can be used as an
optional or first line treatment for chylothorax.
Key word
: Octreotide, Chylothorax

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