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Original ArticleOpen Access
LacCur Stain for Detection of Mucin in Adenocarcinoma
Wattanasirmkit V 
,
Tanboon J ,
Shuangshoti S ,
Shuangshoti S
,
Tanboon J ,
Shuangshoti S ,
Shuangshoti S JANTIMA TANBOON,MD*,
SHANOP SHUANGSHOTI, MD*
Identification of cytoplasmic mucin, usually by Mayer's mucicarmine stain, is one of the
criteria to diagnose adenocarcinoma. The inexpensive LacCur stain, made up of
Curcuma tonga
(khamin-shan) and secreta of
Laccifer lacca
(krang) has been introduced. The aim of this study was
to compare the Mayer's mucicarmine and LacCur stains in the detection of mucin material. The speci-
mens included 17 adenocarcinomas of the stomach, 16 of the colon, 18 of the lung, 16 of the breast, and
12 of the bile duct. Squamous cell carcinoma and hepatocellular carcinoma (altogether 20 cases) were
set as negative control. Like Mayer's mucicarmine, LacCur was capable of detecting of intracyto-
plasmic mucin in all adenocarcinomas of the stomach, colon and bile duct, and revealed mucin sub-
stance in 15/18 and 11/16 cases of specimens from the lung and breast, respectively. The negative con-
trol group showed a negative result. Although a little more time required in preparation, the LacCur
stain is simple and very economical.
Key word : LacCur Stain, Mucin, Adenocarcinoma
SHANOP SHUANGSHOTI, MD*
Identification of cytoplasmic mucin, usually by Mayer's mucicarmine stain, is one of the
criteria to diagnose adenocarcinoma. The inexpensive LacCur stain, made up of
Curcuma tonga
(khamin-shan) and secreta of
Laccifer lacca
(krang) has been introduced. The aim of this study was
to compare the Mayer's mucicarmine and LacCur stains in the detection of mucin material. The speci-
mens included 17 adenocarcinomas of the stomach, 16 of the colon, 18 of the lung, 16 of the breast, and
12 of the bile duct. Squamous cell carcinoma and hepatocellular carcinoma (altogether 20 cases) were
set as negative control. Like Mayer's mucicarmine, LacCur was capable of detecting of intracyto-
plasmic mucin in all adenocarcinomas of the stomach, colon and bile duct, and revealed mucin sub-
stance in 15/18 and 11/16 cases of specimens from the lung and breast, respectively. The negative con-
trol group showed a negative result. Although a little more time required in preparation, the LacCur
stain is simple and very economical.
Key word : LacCur Stain, Mucin, Adenocarcinoma
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