J Med Assoc Thai 2014; 97 (1):101

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The Treatment Outcome of Radical Radiotherapy in Laryngeal Cancer
Chitapanarux I Mail, Tharavichitkul E , Chakrabandhu S , Klunklin P , Onchan W , Pukanhapan N , Srikawin J , Sittitrai P , Vongtama R

Objective: This study reports the treatment outcome of radiotherapy alone for laryngeal cancer.

Material and Method: A retrospective analysis was performed on 138 patients with stage I to IV squamous cell carcinoma of larynx who received radiotherapy alone in Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Thailand between 2003 and 2009.

Results: The 4-year local control (LC) rate in all patients was 44.1%. The 4-year overall survival (OS) was 82.1%. The 4-year LC rates for stage I, II, III, and IV were 75.3%, 69.4%, 57.1%, and 36.9%,respectively (p = 0.0055). Finally, the 4-year OS rates for stage I, II, III, and IV were 85%, 78.6%, 91.1%, and 71.5%, respectively. The laryngeal preservation rate of all stages was 73%.

Conclusion: In conclusion, the treatment outcome of radiotherapy alone in all stages of laryngeal cancer in our center was unsatisfactory when compared to other series.

Keywords: Laryngeal cancer, Radiotherapy alone, Outcome


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