J Med Assoc Thai 2014; 97 (2):153

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Prevalence of Perioperative Asymptomatic Proximal Deep Vein Thrombosis in Thai Gynecologic Cancer Patients
Sermsathanasawadi N Mail, Thangrod R , Hongku K , Wongwanit C , Ruangsetakit C , Chinsakchai K , Leelaphatanadit C , Therasakvichya S , Mutirangura P

Background: Thromboprophylaxis of deep vein thrombosis in gynecologic cancer surgery in Thai patients is not routinely performed.

Objective: The prevalence of perioperative asymptomatic proximal deep vein thrombosis of 100 patients with gynecologic cancer was identified.

Material and Method: Duplex ultrasonography of proximal vein of legs was performed in each patient, seven to 14 days, before and after surgery.

Results: The prevalence of perioperative asymptomatic proximal deep vein thrombosis was 7%. The prevalence of preoperative asymptomatic proximal deep vein thrombosis of legs was 5% and postoperative incidence of asymptomatic proximal deep vein thrombosis of legs was 2.11%. Acute symptomatic pulmonary embolism was found in only one patient. All patients who developed deep vein thrombosis had adenocarcinoma of ovary or uterus, but not cervical cancer. The other risk factors of venous thromboembolism were comparable between deep vein thrombosis and non-deep vein thrombosis group.

Conclusion: The patients with adenocarcinoma of ovary and uterus seem to be the greatest risk of perioperative deep vein thrombosis. High prevalence of venous thromboembolism in gynecologic cancer surgery of Thai patients should be concerned.

Keywords: Asymptomatic disease, Deep vein thrombosis, Female genital neoplasms, Perioperative period, Prevalence


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