J Med Assoc Thai 2008; 91 (5):603

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Cardiac and Hemodynamic Changes during Carbon Dioxide Pneumoperitoneum for Laparoscopic Gynecologic Surgery in Rajavithi Hospital
Kamolpornwijit W Mail, Iamtrirat P , Phupong V

Objective: To study the effects of intraperitoneal CO2 insufflation on cardiopulmonary variables in gynecological
laparoscopic patients.

Material and Method: A prospective descriptive study of BP, HR, End tidal CO2, and Sat O2 in 30 gynecologic
patients who underwent laparoscopic surgery between 1 September 2006 and 30 July 2007.

Blood pressure increased in the early state. The End tidal CO2 significant increased during surgery.
Heart rate and Sat O2 did not change. At completion of the laparoscopic intervention, physiological variables
exhibited a trend to baseline values.

Conclusions: This prospective descriptive study documents significant changes in systemic heamodynamic
variables that seem to be directly associated with the insufflation of CO2 during gynecologic intraperitoneal
laparoscopic surgery. This ongoing evaluation confirms the effect of gynecological laparoscopic surgery and
CO2 insufflation on cardiopulmonary function in patients

Keywords: Laparoscopy, Intraperitoneal space, Gynecologic, Hemodynamic processes, Pneumoperitoneum

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