J Med Assoc Thai 2007; 90 (5):977

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Effectiveness of Recombinant Activated Factor VII (rFVII a) for Controlling Intractable Postpartum Bleeding: Report of Two Cases and Literature Review
Jirapinyo M Mail, Manonai J , Herabutya Y , Chuncharunee S

Background: Recombinant activated factor VII is used for the treatment in patients with inherited or acquired hemophilia with inhibitors and congenital factor VII deficiencies.
Objective: Using recombinant activated factor VII in primary postpartum hemorrhage.
Material and Method: Two cases of women who had postpartum hemorrhage and were treated with recombinant activated factor VII after all conventional treatment failed.
Results: The intractable hemorrhage stopped after treatment with recombinant activated factor VII
Conclusion: The present report showed that massive postpartum hemorrhage that failed to all procedures was controlled successfully by recombinant activated factor VII

Keywords: Intractable postpartum hemorrhage, Recombinant activated factor VII, rFVIIa


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