Material and Method: In the retrospective study, the computer-based medical records of patients of a tertiary care hospital between 1999 and 2013 were reviewed. Univariate and multivariate analyses were used to determine the significant factors predicting the outcomes and IVROBA.

Results: One hundred fourteen patients with brain abscesses were enrolled. The predictive factor of a favorable outcome was Glasgow Coma Scale (GCS) score 13 to 15 (OR 14.64; 95% CI 2.70-79.34; p = 0.02). Conversely, the factors associated with an unfavorable outcome were fungal brain abscess (OR 40.81; 95% CI 3.57-466.49; p = 0.003) and IVROBA (OR 5.50; 95% CI 1.34-22.49; p = 0.017). Moreover, greater distance of the brain abscess from the ventricle decreased the IVROBA (OR 0.62; 95% CI 0.45-0.87; p = 0.005). Abscesses with intraventricular rupture that were at less than 7 mm of a ventricle (p<0.000) were likely to IVROBA.

Conclusion: The outcome of a brain abscess depends on good clinical status, pathogens, and fatal complication of IVROBA. If poor prognostic factors exist, then better surgical option can be selected.

Keywords: Brain abscess, Intraventricular rupture, Ventriculitis, Fungal brain abscess, Predictive factor