Background: Point of care testing using glucose meters that measure capillary blood are the most popular and widely used method for the routine monitoring of blood glucose level. TRUEresult is one of such commonly used blood glucose measuring tools with high accuracy and precision profile according to the manufacturer’s data.

Objective: To evaluate the performance of TRUEresult in real life practice by examining the agreement between capillary and venous glucose result using TRUEresult and a laboratory plasma glucose.

Material and Method: The present study is a cross sectional analytical study. All the data were collected from the patients whose blood samples were drawn for the measurement of plasma glucose at the outpatient department of Srinagarind Hospital, Khon Kaen University, Thailand. TRUEresult blood glucose monitoring system was used to perform blood glucose measurement in whole blood samples from capillary and veins. This was compared with plasma glucose result from the automated analyzer in the central laboratory, which was considered as reference method at Srinagarind Hospital.

Results: The ISO 15197:2013 criteria was used to determine technical accuracy of the TRUEresult tool. Blood glucose levels in whole blood sample from capillary and veins, as measured using the TRUEresult, were 88.24% and 92.16% of the acceptable bias limits. This is below the minimal acceptable criteria. When Parkes error grid analysis was used to define the significance in clinical decision, all the errors of blood glucose levels measured using the TRUEresult were within zone A and zone B, meaning that the errors have no or little influence on clinical decision.

Conclusion: The blood glucose levels in whole blood from capillary and veins measured using TRUEresult blood glucose monitoring was within acceptable accuracy limit. The observed error had no or little influence on clinical decision.

Keywords: Evaluation, Blood glucose measurement, TRUEresult