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Original ArticleOpen Access
Health-Related Quality of Life in Thai Bipolar Disorder
Kongsakon R 
,
Thomyangkoon P ,
Kanchanatawan B ,
Janenawasin S
,
Thomyangkoon P ,
Kanchanatawan B ,
Janenawasin S Background: Bipolar disorder (BPD) affects both patients’ functioning and well-being. Quality of life (QoL)
has gained increasing attention as an important functional outcome in BPD. The present study was conducted
to assess QoL of Thai BPD patients.
Material and Method: The authors obtained cross-sectional demographic, clinical, and functional ratings
from 285 BPD outpatients. SF-36 and Thai Mania Rating Scale (TMRS) were used to assess QoL and severity
of symptoms respectively.
Results: The mean TMRS was 4.42 + 5.87. Compared with the Thai general population, SF-36 scores of study
population were significantly lower, except for bodily pain and social functioning domains. Sodium valproate
treated group’s SF-36 scores was better than lithium carbonate treated group’s (p = 0.02).
Conclusion: The present study is one of the pioneers in assessing the impact of co-morbidity on health-related
QoL in Thai BPD patients. Even in the stable phase, patients were less functioning than the normal Thai
population.
Keywords: Bipolar disorder, Health-related quality of life, SF-36, Lithium, Sodium valproate
has gained increasing attention as an important functional outcome in BPD. The present study was conducted
to assess QoL of Thai BPD patients.
Material and Method: The authors obtained cross-sectional demographic, clinical, and functional ratings
from 285 BPD outpatients. SF-36 and Thai Mania Rating Scale (TMRS) were used to assess QoL and severity
of symptoms respectively.
Results: The mean TMRS was 4.42 + 5.87. Compared with the Thai general population, SF-36 scores of study
population were significantly lower, except for bodily pain and social functioning domains. Sodium valproate
treated group’s SF-36 scores was better than lithium carbonate treated group’s (p = 0.02).
Conclusion: The present study is one of the pioneers in assessing the impact of co-morbidity on health-related
QoL in Thai BPD patients. Even in the stable phase, patients were less functioning than the normal Thai
population.
Keywords: Bipolar disorder, Health-related quality of life, SF-36, Lithium, Sodium valproate
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