We present a 45-years-old suspected systemic lupus erythematosus (SLE) woman who had papulonodular mucinosis
(PNM), without other cutaneous LE lesion. The lesions of PNM distributed on both legs which were an unusual location. In
addition, the renal involvement was found and suspected from lupus nephritis. The patient was treated with prednisolone,
mycofenolate mofetil and chloroquine. After 2 months of follow-up, the renal involvement was improved along with the
disappearance of skin lesions.

Keywords: Papulonodular mucinosis, Systemic lupus erythematosus