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Case ReportOpen Access
Labial Aggressive Angiomyxoma Associated with Endometrial Hyperplasia and Uterine Leiomyoma: A Case Report and Review of the Literature
Larbcharoensub N 
,
Karnsombut P ,
Mathuramon P ,
Tingthanatikul Y
,
Karnsombut P ,
Mathuramon P ,
Tingthanatikul Y A case of aggressive angiomyxoma of the left labia majora in a 48-year-old woman with clinically
presenting progressive enlarged labial mass is reported. The histopathological examination of the lesion
characterized was by fibroblasts, myofibroblasts in the myxoid stroma with prominent thick-walled blood
vessels. The uterus showed intramural leiomyomata with simple hyperplastic endometrium. The labial mass,
uterine leiomyoma and endometrial hyperplasia were immunoreactive for estrogen and progesterone receptors.
Clinical and pathologic features with briefly reviewed relevant literatures were discussed. This is the first
reported description in the literature of synchronous labial angiomyxoma, endometrial hyperplasia, and
uterine leiomyoma.
Keywords: Aggressive angiomyxoma, Endometrial hyperplasia, Leiomyoma, Labia majora, Estrogen
presenting progressive enlarged labial mass is reported. The histopathological examination of the lesion
characterized was by fibroblasts, myofibroblasts in the myxoid stroma with prominent thick-walled blood
vessels. The uterus showed intramural leiomyomata with simple hyperplastic endometrium. The labial mass,
uterine leiomyoma and endometrial hyperplasia were immunoreactive for estrogen and progesterone receptors.
Clinical and pathologic features with briefly reviewed relevant literatures were discussed. This is the first
reported description in the literature of synchronous labial angiomyxoma, endometrial hyperplasia, and
uterine leiomyoma.
Keywords: Aggressive angiomyxoma, Endometrial hyperplasia, Leiomyoma, Labia majora, Estrogen
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