Objective: To compare the minimization of the fog condensation during nasal endoscopy between a commercial anti-fogging agent and baby shampoo.
Material and Method: This randomized double-blinded matched pair study was conducted at the Department of
Otorhinolaryngology, Faculty of Medicine, Khon Kaen University during February 4, 2013 to March 14, 2013. The commercial
anti-fogging solution (Ultrastop®) and baby shampoo solution (Johnson’s® no more tear®) were compared. A computer
generated randomization was performed to select the solution applying on the lens for nasal endoscopy of the right nasal
cavity. The other solution was then used for the left one. Three passes of endoscopy were performed to examine the floor of the
nose, the sphenoethmoidal recess and the middle meatus area which spent about 30 seconds for each time of endoscopy. The
time to become foggy on the lens and the preferred solution assessed by the endoscopists were recorded.
Results: There were 71 eligible patients recruited in the study, 37 males (52.1%) and 34 females (47.9%). There was no
fogging during a 30-second nasal endoscopy either by baby shampoo or commercial anti-fogging solution. However, 9.86%
(95% CI 2.75-16.97) of endoscopists preferred commercial anti-fogging agent, 7.04% (95% CI 0.94-13.14) preferred baby
shampoo and 83.10% (95% CI 74.16-92.03) had equal satisfaction. Both agents had no statistically significant difference for preventing foggy on the lens.
Conclusion: Baby shampoo is an effective agent to prevent fogging during nasal endoscopy and comparable with the
commercial anti-fogging agent.

Keywords: Anti-fogging agent, Baby shampoo, Nasal endoscopy