Views: 1,338 | Downloads:
253
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Original ArticleOpen Access
Prenatal Ultrasonographic Findings in “Trisomy 13”
Pitukkijronnakorn S 
,
Promsonthi P ,
Panburana P ,
Rangsiprakarn R ,
Chittacharoen A
,
Promsonthi P ,
Panburana P ,
Rangsiprakarn R ,
Chittacharoen A Objective: To evaluate the accuracy of prenatal ultrasonographic diagnosis in fetuses with trisomy 13.
Material Method: The present study consisted of all fetuses diagnosed of trisomy 13 and delivered at
Ramathibodi Hospital between 1997 and 2006.
Results: There were 15 cases of trisomy 13. Twelve cases (80.0%) were detected by prenatal ultrasonographic
examination, and 3 cases (20.0%) were missed. Mean maternal age was 31.4 years old. Sixty-six percent were
diagnosed in 2nd trimester (mean 19.4 weeks). The earliest gestational age for detection was 12 weeks 6 days.
The most common abnormal ultrasonographic findings were holoprosencephaly (46.7%), and facial defects
(40.0%).
Conclusion: The accuracy of prenatal sonographic diagnosis in trisomy 13 fetuses was 80%. The most sensitive
prenatal ultrasonographic findings in trisomy 13 were holoprosencephaly and facial defects.
Keywords: Trisomy 13, Prenatal diagnosis, Ultrasonography
Material Method: The present study consisted of all fetuses diagnosed of trisomy 13 and delivered at
Ramathibodi Hospital between 1997 and 2006.
Results: There were 15 cases of trisomy 13. Twelve cases (80.0%) were detected by prenatal ultrasonographic
examination, and 3 cases (20.0%) were missed. Mean maternal age was 31.4 years old. Sixty-six percent were
diagnosed in 2nd trimester (mean 19.4 weeks). The earliest gestational age for detection was 12 weeks 6 days.
The most common abnormal ultrasonographic findings were holoprosencephaly (46.7%), and facial defects
(40.0%).
Conclusion: The accuracy of prenatal sonographic diagnosis in trisomy 13 fetuses was 80%. The most sensitive
prenatal ultrasonographic findings in trisomy 13 were holoprosencephaly and facial defects.
Keywords: Trisomy 13, Prenatal diagnosis, Ultrasonography
Download:
PDF