Views: 1,602 | Downloads:
309
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Original ArticleOpen Access
Antibiotic Prophylaxis for Orthognathic Surgery: A Prospective, Comparative, Randomized Study between Amoxicillin-Clavulanic Acid and Penicillin
Jansisyanont P 
,
Sessirisombat S ,
Sastravaha P ,
Bamroong P
,
Sessirisombat S ,
Sastravaha P ,
Bamroong P Objective: The present study was designed to evaluate the prophylactic efficacy after the correction of dentofacial
deformities between short- and long-term penicillin and amoxicillin-clavulanic acid.
Material and Method: The present study was prospective, randomized, and double blinded. Patients were
separated into four groups randomly: short-term and long-term (5 days) penicillin and short-term and longterm
(5 days) amoxicillin-clavulanic acid.
Results: One hundred twenty two patients were assigned randomly into the four groups. Infection developed
in a patient in the short-term amoxicillin-clavulanic acid group and in a patient in the long-term penicillin
group.
Conclusion: There were no differences in infection between the two groups of antibiotics. Based on the present
study, short-term penicillin is still the most appropriate choice for prophylactic antibiotic in orthognathic
surgery.
Keywords: Antibiotic prophylaxis, Orthognathic surgery
deformities between short- and long-term penicillin and amoxicillin-clavulanic acid.
Material and Method: The present study was prospective, randomized, and double blinded. Patients were
separated into four groups randomly: short-term and long-term (5 days) penicillin and short-term and longterm
(5 days) amoxicillin-clavulanic acid.
Results: One hundred twenty two patients were assigned randomly into the four groups. Infection developed
in a patient in the short-term amoxicillin-clavulanic acid group and in a patient in the long-term penicillin
group.
Conclusion: There were no differences in infection between the two groups of antibiotics. Based on the present
study, short-term penicillin is still the most appropriate choice for prophylactic antibiotic in orthognathic
surgery.
Keywords: Antibiotic prophylaxis, Orthognathic surgery
Download:
PDF