J Med Assoc Thai 2016; 99 (9):178

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Incidence and Prognostic Factors for Mortality of Abdominal Hypertension in Critically Ill Surgical Patients in THAI-SICU Study
Akaraborworn O Mail, Chittawatanarat K , Kongkamol C , Chatmongkolchart S , Kitsiripant C

Objective: This study aimed to investigate the incidence and prognostic factors of mortality in intra-abdominal hypertension
that developed during admission in the surgical intensive care units in Thailand.
Material and Method: This was a prospective observational study in nine university-based surgical intensive care units in
Thailand. (THAI-SICU) The suspected patients who had the intra-abdominal pressure more than 12 mmHg were defined as
intra-abdominal hypertension (IAH). The patients were followed until discharge.
Results: Among 4,652 cases, a total of 71 cases (1.5%) developed IAH. The average age was 53.05+20.26 years. The median APACHE II score was 13 (9-15). Eighteen patients received surgical decompression as treatment. Metabolic acidosis (pH <7.2) and abdominal aortic surgery were the significant factors for mortality in intra-abdominal hypertension patients.
Conclusion: The incidence of intra-abdominal hypertension in the critical surgical care units was low in this cohort. Intraabdominal hypertension in patients who previously received abdominal aortic surgery and who had concomitant acidosis
was the independent risk factor of mortality.

Keywords: Intra-abdominal hypertension, Critical care, Mortality, Compartment syndrome


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