Material and Method: The cross-sectional study was performed between March 2015 and September 2015 at The Princess of Naradhiwas Memorial Hospital. Three hundred ten Thai government officers received annual health check-ups according to standard government protocol. All subjects checked their cognitive performance focus in memory and calculation by physicians. The subjects were divided in two groups according to memory and calculation score, using the cutoff value at tenth percentile. The association between these scores and the clinical parameters were analyzed using Chi-square test for categorical data and t-test for continuous data.

Results: The average age of subjects was 42.93±10.8 years (range 21 to 61 years) with male (91%) predominated. The average of memory and calculation score was 5.72±2.2 (range 0 to 10). The cutoff score was 3.0 (tenth percentile), and 25 (8.1%) subjects were below the cut point score defined as cognitive declined group. The age, alcoholic consumption status, and body mass index greater than 30 were significantly associated with cognitive decline in Thai working aged adult.

Conclusion: The incidence of cognitive decline among Thai working aged adult was 8.1%. The clinical factors that significantly associated with cognitive decline were age, alcoholic consumption status, and body mass index greater than 30.

Keywords: Cognitive decline, Predicting factors