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Material and Method: This was a retrospective comparative study. Data from the medical records and electronic forms of the 208 PCOS women, who consecutively attended the Reproductive between February 2004 and December 2010 were analyzed. According to the recommendation of the AE-PCOS society, the subjects were classified into three groups of CVD risk.
Results: There were 22, 129, and 57 women being at optimal risk, at risk, and at high-risk groups, respectively. There were significant differences in all metabolic factors between the different CVD classifications according to the AE-PCOS society. Furthermore, the PCOS women at high-risk had higher rates of the most significant parameters than those at risk. However, the LDL-C levels were not different between PCOS women at high-risk and at risk. Interestingly, 56%, 90.7%, and 100% of PCOS women at risk, at high-risk, and at high-risk plus other risks, respectively, had LDL-C levels above the target goals, which needed to be lower for the primary CVD prevention according to the AE- PCOS society recommendation.
Conclusion: There were differences in all metabolic factors between the different CVD classifications, but LDL-C levels were not different between PCOS women at high-risk and at risk. To get target goal for the primary CVD prevention, 91% and 100% of PCOS women at high-risk and at high-risk plus other risks need to lower LDL-C levels.
Keywords: CVD risk classification, LDL-C level, Metabolic parameters, Polycystic ovary syndrome