Background: Post-burn hypertrophic scars are prevalent and they can cause significant functional and cosmetic impairment.
Previous literatures has shown the beneficial effect of silicone gel sheet in treatment of hypertrophic scars but the literatures
reported benefits in the original product which is more expensive and have the effects on financial burden of the patients that results in high cost of treatment.
Objective: To compare efficacy of silicone gel sheet between commercial brands of silicone gel sheet, Cicacare® and Actewound®, on post-burn hypertrophic scar.
Material and Method: Prospective randomized controlled trial was conducted in 30 patients with second to third degree burns with post-burn hypertrophic scar. Vancouver scar scale (VSS) was evaluated at 0, 2, 4, 8, 12, 16, 20, 24 weeks after treatment.
Results: No difference in pigmentation, pliability, pain, itching, vascularity, height, Vancouver scar scale (VSS) and satisfaction
(physical appearance, adhesive properties, ease of application, patient comfort, uniform with skin, durability) between commercial brands of silicone gel sheet, Cicacare® and Actewound® groups (p>0.05). Both commercial brands of silicone gel sheets demonstrated comparable results; however the cost of treatment is less expensive with Actewound®.
Conclusion: Actewound® can be used as alternative, more affordable choice for management of post-burn hypertrophic scar.

Keywords: Silicone gel sheets, Hypertrophic scar, Post-burn scar, Scar treatment, Burns