Materials and Methods: Prospective randomized control trial was conducted by two treatment groups (n = 10 each) for eight-week duration. Sleep-related parameters consisted of the Clinical Global Impression - severity [CGI-S], the Pittsburgh Sleep Quality Index-Thai version [Thai-PSQI], the Hospital Anxiety and Depression Scale Thai version [Thai HADS] and the Philadelphia Mindfulness Scale [PHLMS] were collected before and after both treatments.

Results: Mindfulness-based group had statistically significant improvement of better sleep quality and clinical impression improvement-severity (p-value 0.0032 and <0.0001, respectively). Mindfulness level and sleep profiles improved, although there was no significant difference when both treatments were compared.

Conclusion: Mindfulness-based intervention improves sleep quality, and could be decreased impact of daily-life stress and lowered severity of insomnia symptoms.

Keywords: Mindfulness, Sleep disturbance, Insomnia, Thai-PSQI, CGI-S, PHLMS, Thai HADS, CBT-I