Objective: To determine the frequency and clinical characteristics of patients with malignant eyelid tumors at Srinagarind Hospital between January 2000 and January 2017.

Materials and Methods: This retrospective descriptive analysis was conducted by review medical record. A computerized retrieval system was used to identify all patients whose surgical pathologic results diagnosed as malignant eyelid tumors between January 2000 and January 2017. The patient’s medical records, including the patient’s gender, age of presentation, and underlying disease were collected. Tumor locations, histopathologic results, treatments, and time of recurrences were recorded.

Results: One hundred twenty-six patients that had one tumor each, were studied. There were more malignant tumors in female. The median age of presentation was 67.0 years, whereas the mean age was 65.6 years (range 28 to 96 years). Tumors developed most commonly on the lower eyelid (n = 56; 44.4%) and less on the upper eyelid (n = 40; 31.7%). Of the 126 malignant tumors, 75 were basal cell carcinomas (59.5%, 95% CI 50.9 to 68.1), 25 were squamous cell carcinomas (19.8%), and 15 were sebaceous gland carcinomas (11.9%). The clinical accuracy in predicting eyelid malignancy was 65.9%. Only 26.2% of patients had more than a one-year follow-up and no patient had more than five years of follow-up.

Conclusion: Basal cell carcinoma was the most common malignant eyelid tumor in Northeast Thailand. The frequency of sebaceous gland carcinoma in the present region was significantly more than the previous studies in a Caucasian population.

Keywords: Eye, Eyelid, Malignant, Tumor