J Med Assoc Thai 2007; 90 (1):149

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The Development and Validation of a Diabetes Risk Score for High-Risk Thai Adults
Keesukphan P Mail, Chanprasertyothin S , Ongphiphadhanakul B , Puavilai G

Objective: To develop a simple risk score to identify high-risk individuals for diabetes screening in Thailand.

Material and Method: The authors analyzed data from 75-g oral glucose tolerance tests performed in 159 males and 270 females, aged 48.4±10.9 years.

Results: The independent variables associated with diabetes included age (p<0.001), BMI (p<0.01) and known history of hypertension (HHT) (p<0.01). The risk equation was Y = 3age + 5BMI +50HHT. At the cut-off Y value of 240, the sensitivity and specificity for having diabetes were 96.8% and 24.0%, respectively. The positive predictive value was 17.8% and the negative predictive value was 97.8%. Using the equation in a validation group comprising 1617 subjects, it was found that 560 (34.6%) diabetes screenings could be saved while 28 subjects (12.8%) with diabetes would be missed.

Conclusion: The authors have developed a simple risk scoring method that should be helpful in decreasing the number of unnecessary screening and optimizing the costs associated with diabetes screening.

Keywords: Diabetes screening, Risk score


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