A 49-year-old woman presented with complete heart block and recurrent syncope, which had caused a left fibula fracture. Transthoracic echocardiography showed a large right atrial mass. She received an emergency operation due to signs of tumor obstruction. A tumor was found originating from the inferior vena cava (IVC). Partial tumor removal was performed. A postoperative computed tomography scan revealed a uterine mass and tumor extension along the IVC. The pathological report confirmed a diagnosis of leiomyoma with intracardiac extension. She underwent residual IVC tumor removal under cardiopulmonary bypass using the deep hypothermic circulatory arrest technique. The patient was scheduled for a hysterectomy and bilateral salpingo-oophorectomy two months later and recovered uneventfully.

Keywords: Intravenous leiomyoma, Intracardiac extension leiomyoma, Cardiopulmonary bypass, Deep hypothermic circulatory arrest