Objective: To retrospectively assess whether the size of renal cyst in autosomal dominant polycystic kidney disease (ADPKD) patient correlated with the cystic lesion in visceral organs and enlargement of visceral organ.

Materials and Methods: The Institutional Review Board approval was obtained for the present study. The authors measured the size of renal cysts from 85 abdominal ultrasound images, and CT studies randomly sampled from Thai population. The dataset had been verified by two certified radiologists within the last ten years. Additionally, the authors also collected the size of the largest liver cyst, the amount of liver cyst, splenomegaly, the amount of pancreas and splenic cyst, adrenal lesion, hepatomegaly, splenomegaly, the size of liver, paraaortic lymphadenopathy, and fatty change of liver. The present study used ANOVA, and t-test to analyze the results with p-value of less than 0.05 to infer a statistically significant difference.

Results: There was correlation between the size of renal cysts and the size of liver cysts, as well as the amount of liver cysts within the authors’ dataset of 85 samples. Correlation coefficient (r) of 0.3 was chosen as weak positive correlation. Moreover, the size of renal cysts also correlated with hepatomegaly. Nonetheless, gender, age group, pancreatic cyst, adrenal lesion, splenic cyst, splenomegaly, fatty liver, and paraaortic lymphadenopathy showed no significant correlation.

Conclusion: There is a strong correlation between the size of the largest liver cyst, amount of liver cysts, and hepatomegaly compared with the size of the largest renal cyst. Other factors showed no significant correlation. Nonetheless, when the size of liver cysts and the amount of liver cysts increase, the size of liver span always increase.

Keywords: Liver cyst, ADPKD, Renal cyst, Retrospective studies

Received 13 Feb 2019 | Revised 19 Apr 2019 | Accepted 23 Apr 2019