| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
,
Taneepanichskul N ,
Siriwong W ,
Pitaknoppakul N ,
Lohsoonthorn V Objective: To examine the association of long-term exposure to household indoor PM of less than 10 micrometer [PM10] and increased carotid intima-media thickness [CIMT] of the common carotid artery [CCA].
Materials and Methods: A one-year follow-up study was conducted in 104 households located in the central city of Sakon Nakhon province, Thailand. Clinical testing and a carotid artery ultrasound of participants were undertaken between September 2016 and September 2017. Household PM10 concentrations, temperature, and relative humidity [RH] were measured inside the participants’ home during the wet and dry seasons.
Results: The average of PM10 concentrations was 24.2±11.2 μg/m3. Mean and maximum CIMT at CCA was different between baseline and follow-up (p-value <0.001). Logistics regression models showed that an increase of 1 μg/m3 average household PM10 concentrations were associated with 6% increased risk of increased maximum CIMT of CCA (AOR 1.06; 95% CI 1.02 to 1.11).
Conclusion: Household PM10 concentration is associated with increased CIMT of CCA. This finding suggests that household PM10 may be a risk factor for CVD morbidity and mortality.
Keywords: Household air pollution, PM less than 10 micrometer [PM10], Carotid intima-media thickness [CIMT], Common carotid artery [CCA], Cardiovascular disease [CVD]