Objective: Brain metastasis is common in various solid organ tumors and the prognosis is unfavorable. The objectives were
to characterize brain metastasis patients and to study the Recursive Partition Analysis (RPA) classification as a predictor of
survival.
Materials and Methods: This is a retrospective analytic study, which includes 213 adult patients diagnosed with brain metastasis from solid organ tumors in Srinagarind Hospital during 2006-2010. The clinical characteristics and treatment outcome were reviewed.
Results: The median survival time was 3.5 months (95% CI: 2.75-4.35). The overall survival rates at 1, 2, and 5 years were
21.6%, 8.9%, and 4.2% respectively. The 10-year survival rate was 3.1%. The independent risk factors for having inferior
survival were male gender and RPA class III.
Conclusion: Brain metastasis is common in lung and breast cancer and the overall survival time is short. RPA class is a simple and important prognostic factor for survival.

Keywords: brain neoplasm, brain metastasis, prognostic score, whole brain radiotherapy (WBRT), RPA