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Intravascular lymphoma is a rare type of lymphoma with a poor prognosis. Patients most often present with cutaneous or central nervous system findings. Its early diagnosis appears very important since it may be curable with appropriate chemotherapy regimens. A 61-year-old man who initially presented with diffuse arborizing telangiectasia on
normal-appearing skin and limb edema is described. Skin biopsy and immunohistochemical studies confirmed intravascular B-cell lymphoma. After eight courses of treatment with combination chemotherapy (rituximab, cyclophosphamide, adriamycin, vincristine, and prednisolone) the outcome was complete remission after an 18-month follow-up.
Keywords: Intravascular lymphoma, B-cell, Telangiectasia