The purpose of the present study was to examine the association between abnormal hepatocellular
functions and abnormal fasting glucose level in the employees in a university hospital in Bangkok, Thailand.
A cross-sectional data analysis was conducted among 2,790 workers who were 35-60 years old and participated
in both the annual fasting plasma glucose(FPG) examination and the baseline questionnaire survey during
2001-2005. The prevalence rates (95% confidence interval; CI) of impaired fasting glucose (IFG) were
10.4(9.1-11.7) and 20.3(17.0-23.9) percent respectively for women and men, while those of type 2 diabetes
were 3.1(2.4-3.9) and 6.5 (4.6-8.9) respectively. After controlling for conventional risk factors, only the
alanine aminotransferase (ALT) level was significantly associated with increased abnormal FPG. This
association was particularly obvious for the DM. In conclusion, the present study demonstrated that the
type 2 diabetes and ALT association was also evident in the Thai population.

Keywords: Alanine transaminase, Aspartate aminotransferases, Diabetes mellitus, type 2, Glucose intolerance,
Hospitals, university, Personnel, hospital