Impact of Left Ventricular Systolic Function on Hospital Mortality in Patients Undergoing Percutaneous Coronary Intervention: Results from Thai Percutaneous Coronary Intervention Registry (TPCIR)
Chaiyasith Wongvipaporn MD*, Songsak Kiatchoosakun MD*, for TPCIR group
Affiliation : * Division of Cardiology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Objective : To investigate the relationship between left ventricular (LV) systolic function and the clinical outcomes in
unselected patients underwent percutaneous coronary intervention (PCI), through analysis of the Thai Percutaneous
Coronary Intervention Registry (TPCIR).
Material and Method: The association between LV systolic function and in-hospital mortality in 2,427 patients undergoing
PCI included in TPCIR between May and October 2006, was studied. Patients were categorized as either left ventricular
ejection fraction (LVEF) less than 40% or LVEF 40% or more.
Results : In-hospital mortality was 8.0% among patients with LVEF less than 40% and 1.3% in those with LVEF of 40%
or more. After adjustment for baseline variables, those associated with increased hospital mortality were, LVEF less than
40% (OR = 2.87, 95% CI = 1.57 to 5.23), p<0.001, history of heart failure (OR = 15.99, 95% CI = 8.10 to 31.56, p<0.001),
previous stroke (OR = 66.96, 95% CI = 11.01 to 407.36, p<0.001), and extent of coronary artery disease (OR = 2.12,
95% CI = 1.04 to 4.32, p = 0.038).
Conclusion : The results of the present study suggest that LV systolic function, and history of heart failure within two weeks
may increase in-hospital mortality following PCI in unselected patients and across all indications for PCI. Assessing LV
function before PCI appears warranted.
Keywords : PCI, Left ventricular systolic function
