Chemotherapy-Related Cerebral Venous Sinus
Thrombosis in a Colon Cancer Patient Receiving Adjuvant
Chemotherapy:
Case Report: and Literature Review
Chanida Vinayanuwattikun MD, PhD¹, Nutchawan Jittapiromsak MD², Iyavut Thaipisuttikul MD¹
Affiliation : ¹ Department of Medicine, Faculty of Medicine, Chulalongkorn University and the King Chulalongkorn Memorial Hospital, Bangkok, Thailand ² Department of Radiology, Faculty of Medicine, Chulalongkorn University and the King Chulalongkorn Memorial Hospital, Bangkok, Thailand
Oxaliplatin-combination treatment has been adopted as a standard adjuvant treatment for high-risk stage II and stage III colorectal cancer. Cerebral
venous sinus thrombosis (CVST) is a serious adverse event related to this combination treatment. The benefits of this combination treatment
outweigh the risks, yet some physicians are reluctant to resume the treatment after the clot has resolved. The authors reported a case of CVST,
and the success in resolving this situation with the use of a secondary prophylaxis, a low-molecular weight heparin.
Received 15 March 2021 | Revised 18 June 2021 | Accepted 23 June 2021
doi.org/10.35755/jmedassocthai.2021.12.12675
Keywords : Oxaliplatin; Central venous sinus thrombosis; Chemotherapy-induced VTE
