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Lamotrigine-induced Stevens–Johnson Syndrome Coexisting with Seborrheic Dermatitis in a Dengue virus-infected Patient: A Case Report

Rithee Smithrithee1, Piyakan Limtanyakul1, Rasthawathana Desomchoke1

Affiliation : 1 Division of Dermatology, Chulabhorn Hospital, Chulabhorn Royal Academy, Bangkok, Thailand

Stevens-Johnson syndrome is a serious skin condition. Lamotrigine-induced Stevens-Johnson syndrome is strongly associated with HLA*B1502 in the Thai population. Stevens-Johnson syndrome has never been reported to coexist with other skin diseases. Here, the authors report a case of Stevens–Johnson syndrome with severe seborrheic dermatitis in a Dengue virusinfected patient. The patient was treated with a high-dose systemic corticosteroid and has shown an excellent response to therapy.

doi.org/10.35755/jmedassocthai.2021.S02.12794

Keywords : Dengue virl infection, Seborrheic dermatitis, Stevens–Johnson syndrome, Lamotrigine, IL-17, Cytokine Case Report


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