Perinatal Outcomes in Severe Preeclamptic Women between 24-33+6 Weeks’ Gestation
Sujittra Jantasing MD*, Somchai Tanawattanacharoen MD**
Affiliation : * Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok ** Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok
Objective : The present study was undertaken to determine perinatal and maternal outcomes in severe pre-
eclamptic women between 24 - 33 -week gestation and compare the outcomes between expectant and aggres-
sive management.
Material and Method: A retrospective descriptive study of 99 women with severe preeclampsia between 24-
33+6-week gestation who delivered at the King Chulalongkorn Memorial Hospital from January 2002 to
December 2005 was included. The outcomes were analyzed according to the gestational age at the time of
admission (< 28 weeks’ and > 28 weeks’ gestation) according to expectant compared with aggressive
management. Statistical analysis was performed by student t-test and x2 - test.
Results : The perinatal morbidity and mortality were significantly high in the gestational age < 28 weeks
group. There were 11 perinatal deaths, 8 in those managed at < 28 weeks and 3 in those managed at 28-29
weeks’ gestation (p < 0.05). Maternal morbidities were similar among both groups. There was no maternal
death.
Conclusion : Delivery at remote from term, especially < 2-week gestation, increases neonatal morbidity and
mortality in severe preeclamptic women. Expectant management should be done in the tertiary care center
with close maternal and fetal monitering.
Keywords : Perinatal outcomes, Maternal outcomes, Severe preeclampsia, Expectant management, Aggressive management
