Labial Aggressive Angiomyxoma Associated with Endometrial Hyperplasia and Uterine Leiomyoma: A Case Report and Review of the Literature
Noppadol Larbcharoensub MD*, Patcharee Karnsombut, Cert. MLT*, Piyanun Mathuramon MD*, Yada Tingthanatikul MD**,
Affiliation : * Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok ** Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok
A case of aggressive angiomyxoma of the left labia majora in a 48-year-old woman with clinically presenting progressive enlarged labial mass is reported. The histopathological examination of the lesion characterized was by fibroblasts, myofibroblasts in the myxoid stroma with prominent thick-walled blood vessels. The uterus showed intramural leiomyomata with simple hyperplastic endometrium. The labial mass, uterine leiomyoma and endometrial hyperplasia were immunoreactive for estrogen and progesterone receptors. Clinical and pathologic features with briefly reviewed relevant literatures were discussed. This is the first reported description in the literature of synchronous labial angiomyxoma, endometrial hyperplasia, and uterine leiomyoma.
Keywords : Aggressive angiomyxoma, Endometrial hyperplasia, Leiomyoma, Labia majora, Estrogen
