Comparison between Adenocarcinoma in both Endocervical and Endometrial Specimens from Fractional Curettage and Pathologic Findings in Subsequent Hysterectomy Specimens
Patou Tantbirojn MD*, Surang Triratanachat MD*, Prasert Trivijitsilp MD*, Somchai Niruthisard MD*
Affiliation : * Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok
Objective : To evaluate the hysterectomy specimen findings in the patients who underwent fractional curettage
(F&C) with presence of adenocarcinoma in both endocervical and endometrial specimens.
Material and Method: Forty-one patients who had adenocarcinoma in both endocervical and endometrial
specimens from F&C and underwent subsequent hysterectomy for surgical staging without pre-operative
radiotherapy or chemotherapy at King Chulalongkorn Memorial Hospital between 1999 and 2007 were
evaluated. Histologic slides from both F&C and hysterectomy specimens were reviewed and assessed. All
cases of endometrial adenocarcinoma with cervical involvement (stage 2) in hysterectomy specimens were
also assessed and compared to the results in F&C specimens.
Results : Fifteen patients (36.6%) with both positive endocervical and endometrial specimens from F&C were
diagnosed as endometrial adenocarcinoma within uterine cavity with lower uterine segment involvement.
Only 34.1% of cases were endometrial carcinomas with cervical involvement. In the 35 cases with endometrial
carcinoma stage 2, 60% had adenocarcinoma in both endocervical and endometrial specimens from F&C.
Conclusion : In the patients who had adenocarcinoma in both endocervical and endometrial specimens from
fractional curettage, the most common final pathological diagnosis from hysterectomy specimens was
endometrial adenocarcinoma within uterine cavity with lower uterine segment involvement. Therefore,
only 60% of endometrial carcinoma stage 2 revealed positive adenocarcinoma in both endocervical and
endometrial specimens from fractional curettage.
Keywords : Endometrial adenocarcinoma, Fractional curettage
