Serial Evaluation of the MODS, SOFA and LOD Scores to Predict ICU Mortality in Mixed Critically Ill Patients
Bodin Khwannimit MD*
Affiliation : * Division of Critical Care, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla
Objective : To perform a serial assessment and compare ability in predicting the intensive care unit (ICU)
mortality of the multiple organ dysfunction score (MODS), sequential organ failure assessment (SOFA) and
logistic organ dysfunction (LOD) score.
Material and Method: The data were collected prospectively on consecutive ICU admissions over a 24-month
period at a tertiary referral university hospital. The MODS, SOFA, and LOD scores were calculated on initial
and repeated every 24 hrs.
Results : Two thousand fifty four patients were enrolled in the present study. The maximum and Δ-scores of all
the organ dysfunction scores correlated with ICU mortality. The maximum score of all models had better
ability for predicting ICU mortality than initial or delta score. The areas under the receiver operating
characteristic curve (AUC) for maximum scores was 0.892 for the MODS, 0.907 for the SOFA, and 0.92 for the
LOD. No statistical difference existed between all maximum scores and Acute Physiology and Chronic Health
Evaluation II (APACHE II) score.
Conclusion : Serial assessment of organ dysfunction during the ICU stay is reliable with ICU mortality. The
maximum scores is the best discrimination comparable with APACHE II score in predicting ICU mortality.
Keywords : Multiple organ failure, Organ dysfunction score, Intensive care, Critical illness, Severity of illness
