Tissue Imprint for Intra-operative Evaluation of Musculoskeletal Tumors
Taweechok Wisanuyotin MD*, Jumpol Mitchai MD**, Winai Sirichativapee MD*, Weerachai Kosuwon MD*, Chat Sumnanoont MD*, Polasak Jeeravipoolvarn MD*
Affiliation : * Department of Orthopaedics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand ** Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Objective : To evaluate the usefulness of an intra-operative tissue imprint as a role to provide a provisional
diagnosis in patients with musculoskeletal tumors.
Material and Method: 118 patients underwent surgical treatment for musculoskeletal tumors. Tissue imprints
from suspected tissues were conducted in all of the patients and the results were compared with the final
permanent section.
Results : The usefulness of the imprint slides (i.e., the diagnostic yield) was 88.14%. The respective, overall
sensitivity, specificity, accuracy, positive and negative predictive value was 93.75%, 100%, 96.15%, 100%
and 90.90%.
Conclusion : Tissue imprinting is a useful method for intra-operative evaluation of adequacy and provides a
provisional diagnosis of the musculoskeletal tumors lesions.
Keywords : Bone neoplasms, Cytodiagnosis, Musculoskeletal tumors, Intra-operative period
