Health Risk Assessment of Inorganic Arsenic Intake of Ronphibun Residents via Duplicate Diet Study
Piyawat Saipan DVM, MSc*, Suthep Ruangwises BSc, PhD*
Affiliation : * Department of Veterinary Public Health, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand
Objective : To assess health risk from exposure to inorganic arsenic via duplicate portion sampling method in
Ronphibun residents.
Material and Method: A hundred and forty samples (140 subject-days) were collected from participants in
Ronphibun sub-district. Inorganic arsenic in duplicate diet sample was determined by acid digestion and
hydride generation-atomic absorption spectrometry. Deterministic risk assessment is referenced throughout
the present paper using United States Environmental Protection Agency (U.S. EPA) guidelines.
Results : The average daily dose and lifetime average daily dose of inorganic arsenic via duplicate diet were
0.0021 mg/kg/d and 0.00084 mg/kg/d, respectively. The risk estimates in terms of hazard quotient was 6.98
and cancer risk was 1.26 x 10-3.
Conclusion : The results of deterministic risk characterization both hazard quotient and cancer risk from
exposure inorganic arsenic in duplicate diets were greater than safety risk levels of hazard quotient (1) and
cancer risk (1 x 10-4).
Keywords : Inorganic Arsenic, Duplicate Diet, Risk Assessment, Ronphibun
